Yale University, Molecular Biophysics & Biochemistry
Creating Novel Proteins by Selection and Design
Protein design approaches have revealed many fundamental features of protein structure and stability. Moreover, we are now in the era that the early work presaged – the design of new proteins with practical applications and uses. In this talk I will briefly survey some past milestones, but mostly I will present the results of our most recent work. My talk will encompass first principles computational design, ‘bioinfomatics’ informed design, and design augmented by the use of in vivo selections and screens.
Venue: Waddington seminar room (1.08)
Host: Sander Granneman